From: liux (liux$##$med.usyd.edu.au)
Date: Mon Jul 26 1999 - 03:36:40 EDT
I got stuck in obtaining a little simple compound---
4-iodophenethylamine. Following some literature I tried a few ways,
starting from 4-iodotoluene led to 4-iodophenylacetonitrile via
bromide, but reduction of the nitrile (with either LAH or NaBH4) always
ended up with a mixture of and fairly low yield. Is there any chemical
reduce nitrile into amine without getting the iodine off aromatic ring?
Can any of you think about this and give me some advice on alternative
Many thanks in advance.
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